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This gene encodes a transcription factor that belongs to your homeobox gene family. Genes of the relatives are extremely conserved amongst vertebrates and important for vertebrate embryonic advancement. This gene continues to be implicated in fetal pores and skin development and cutaneous regeneration.

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In mice, the same gene was proven to show temporal and spatial colinearity in the most crucial human body axis with the embryo, but was not expressed in the secondary axes, which implies features in physique patterning together the axis. This gene as well as other HOXB genes form a gene cluster on chromosome seventeen inside the 17q21-22 location.[6]

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